Cimidona® – Ze 450
For the treatment menopausal complaints with symptoms such as hot flushes, insomnia, irritability, fatigue and depressive mood.
Cimidona®: 6.5 mg of dry extract Ze 450 from Cimicifuga racemosa L. rhizome
Cimidona forte®: 13 mg of dry extract Ze 450 from Cimicifuga racemosa L. rhizome
Drug-extract ratio (DER): 4.5-8.5:1
Extraction solvent: 60% Ethanol (V/V)
Standardized extract with minimum of 6 % (m/m) triterpene glycosides
Cimidona®: 1 tablet per day.
Cimidona forte®: 1 tablet per day.
Recommended for minimum of 6 weeks.
Clinical Evidence & Mode of action
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Ze 450 – The Difference
Most prescribed – Ze 450 is the No.1 treatment for menopausal disorders in Switzerland
Proven clinical efficacy – A number of placebo-controlled and observational studies prove the efficacy and safety of Ze 450 for a wide range of menopausal symptoms
Natural therapy – Menopause relief without synthetic or natural hormones
Extremely safe and tolerable – Good safety record and no clinically relevant drug-drug interactions
Suitable for breast cancer patients – No hormonal effect and no reported risk for breast cancer
Special extract – Black cohosh product with highest API content (13 mg Ze 450 extract) on market
Individual treatment – Dose-dependent treatment for patients with mild to moderate symptoms (6.5 mg) and moderate to severe symptoms (13 mg)